After 10 years in the U. K. with ICI Pharmaceuticals, Ian returned to Ireland as Managing Director of Cullen & Davidson, a small company specializing in retail pharmaceuticals.In 1980 Ian and two partners founded the Institute of Clinical Pharmacology in Dublin. The company went public in 1984 on NASDAQ and this necessitated the emigration of the Brick family to the USA. The company was engaged in worldwide clinical trials of newly discovered pharmaceutical compounds particularly in the HIV research field. Ian and Katherine moved to Nashville in 1987.n 1990 Ian founded Pharmaceutical Laboratory Services in Baltimore, Maryland, which was subsequently purchased byhismajor competitor in 1994.
Katherine along with Ian initiated a Sister Cities link between Belfast, and Nashville, Tennessee which has resulted in the annual Belfast/Nashville Songwriters Festival. She encouraged tourism, cultural and economic ties between the two cities.